Water-Soluble Cannabidiol Proves Best for CBD Absorption
Researchers affiliated with Colorado State University recently published the results of a study to determine how CBD is best absorbed. They compared the absorption of CBD blended with medium-chain triglycerides (MCT) coconut oil, CBD isolate and three types of water-soluble CBD.
The researchers’ goal was to determine how each type of CBD product entered and left the bloodstream and the rate at which CBD was processed. The study also documented how the CBD products interact with the liver and whether food consumption and metabolism impacted CBD absorption.
Fourteen men were study participants, and the study results were published in the peer-reviewed journal Nutrients. The results made it clear that water-soluble CBD products have better CBD absorption compared to oil-based CBD. There was a more than 500 percent difference between the maximum blood concentration realized when taking water-soluble versus oil-based CBD and CBD isolate.
Another finding emerging from the study was that CBD products should be consumed with food for maximum absorption. The researchers found that CBD concentration in the bloodstream was three times higher when taken with food compared to taking the product on an empty stomach.
A third finding was that water-soluble CBD also appeared to modify early triglyceride and insulin responses. Chief Medical Officer at the company which produces water-soluble CBD products wrote,
“Our study results show that within 30 minutes after eating a meal, CBD appeared to lower insulin and triglyceride levels. The exact mechanism of how CBD impacts insulin levels and triglyceride levels is unclear as the CBD levels 30 min post-meal are very low. What one can infer from these findings is that CBD may have a favorable effect on how fats and sugars are metabolized after a meal so CBD might be beneficial for supporting healthy glucose and lipid metabolism.”
A fourth finding was that average doses of CBD of 30 mg do not appear to impact liver and kidney functioning.
Pharmacokinetics is the science of how bioactives are absorbed throughout the body. Research in this area compares the consumption of a bioactive compound versus what is absorbed and the rate and efficiency of the absorption. This particular study included CBD water-soluble CBD products. The main idea of the research was to identify how its customers can get the most benefits from CBD products.
Though CBD products are not evaluated by the FDA, there is growing scientific evidence that they may deliver important health and wellness benefits. This new study broadens the understanding of how CBD works in the body. This is one of the first research projects to study whether CBD should be taken with or without food. This information can benefit everyone because it guides the best practices for maximizing CBD absorption.